Vitamin B6 in the treatment of the premenstrual syndrome
A search of the literature yielded 12 controlled trials on vitamin B6 in the treatment of the premenstrual syndrome. These are discussed with emphasis on methodological aspects. A major drawback of the trials is the limited number of patients included. The existing evidence of positive effects of vitamin B6 is weak, and some well-designed trials with positive results would be needed to change this view.
Kleijnen J, Ter Riet G, Knipschild P:
Br J Obstet Gynaecol 97(9): 847-852, 1990 2242373